ODESSA - Maria Medrano, 62, passed away on Sunday, April 22, 2018, at Medical Center Hospital in Odessa, TX. Maria was born in Matamoros, Tamalaulipas, Mexico on February 5th, 1956 to Jose Maria Castro and Cipriana Sanchez. She married Miguel Angel Medrano when she was a young adult and they raised eight children together in Weslaco. Maria was a homemaker and the perfect mother. She loved to cook and care for her children and grandchildren. Maria loved working in her garden and always kept beautiful roses. She loved her precious german sheperds. When she wasn't busy caring for the house and children, she loved to play loteria with her friends. Maria is preceded in death by her parents Jose and Maria Castro. She is survived by her children, Jimmy Escalantes (Veronica), Jesse Sanchez (Norma), Judy Flores (Ruben), Miguel Angel Medrano Jr. (Perla), Larry Medrano (Ivette), Justin Medrano (Veronica), Maryann Medrano (Jose), and Marlene Medrano, all of Odessa, Texas, 26 grandchildren, Javier Lopez Jr., Jimmy Escalantes Jr., Melanie L. Sanchez, Ashlee A. Sanchez, Yahaira Escalantes, Miguel A. Medrano III, Larry Medrano Jr., Lee Roy Flores, Jesse Sanchez Jr., Rhiana Medrano, Ruben Lee Flores, James Escalantes, Nathan Medrano, April Sanchez, Justin Medrano Jr., Rita Medrano, Melissa Medrano, Kayley Tovar, Citali Sanchez, Josylin Tovar, Emily Medrano, Ethan Medrano, Ivan A. Flores, Jayden X Sanchez, Aleyda Escalantes, and Anna Marie Tovar. She will always be remembered as a loving and caring wife, mother, grandmother and great-grandmother, who put her families needs ahead of her own. She set an example of hard work, ethics and faith.